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Single Nucleotide Polymorphisms / Methods and Protocols (Полиморфизм нуклеотида / методы и протоколы) Kwok Pui-Yan,  Springer

Kwok Pui-Yan
Single Nucleotide Polymorphisms / Methods and Protocols (Полиморфизм нуклеотида / методы и протоколы)



Автор: Kwok Pui-Yan
Название: Single Nucleotide Polymorphisms / Methods and Protocols (Полиморфизм нуклеотида / методы и протоколы)
Издательство: Springer
Классификация: ИНОСТРАННЫЕ ЯЗЫКИ , ПРОФЕССИОНАЛЬНАЯ И НАУЧНАЯ ЛИТЕРАТУРА
ISBN: 0896039684
ISBN-13(EAN): 9780896039681
Обложка: Hardcover
Страницы: 288
Дата издания: 2003
Круг читателей: преподаватели и специалисты
Описание: Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Дополнительное описание: Springer

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